What is Nattopur?
Nattopur assists people with thrombosis by providing nutrients to maintain normal
blood cholesterol levels and subsequently reduce blood clots in the blood vessels.
Thrombosis: The Silent Killer
Thrombosis is the formation of a blood clot (thrombus) inside a blood vessel,
which leads to the obstruction of blood flow through the body. Lack of blood and,
consequently, oxygen supply may result in severe tissue damage and organ
failure. Thrombosis can happen in any blood vessel in the body and is thus
classified based on the location of the body it occurs in; examples include venous
thrombosis, arterial thrombosis, and microthrombosis. However, the prevalence
of venous thrombosis is four times higher than arterial thrombosis.
Complications from Hypertension
Hypertension, otherwise known as high blood pressure, occurs when there is a
hardening of arteries and the heart works harder to pump blood to the body.
When blood is forced through, the high pressure can rupture molecules and
cause the body to overreact and form unnecessary clots. This means that
elevated blood pressure in the arteries is a major risk factor for cardiovascular
diseases, such as a stroke or myocardinal infarction (more commonly known as
a heart attack). It can also lead to hypertensive retionopathy and nephropathy.
Hypertension’s significant impact on health means it can cause renal disease in
addition to heart disease, making it one of the leading top ten causes of death.
Worldwide, 1 out of 3 deaths is caused by ischemic heart diseases and since
2000, a heart attack has become the leading cause of death in the world with a
stroke ranked closely as the second.
What is Natto?
Natto is fermented soybeans and has been a part of the Japanese cuisine for
over a thousand years, believed to be health enhancing. Dr. Hiroyuki Sumi, a
Japanese medical researcher, discovered in 1980 that natto had effective
antithrombotic properties. The extraction of the enzyme produced during the
fermentation of natto was coined as nattokinase, and it has demonstrated strong
activities against thrombosis.
The Actions of Nattokinase
Since nattokinase can be consumed orally, it uses the following three diverse
physiological and cellular pathways to increase the body’s defense against
thrombosis:
1. Nattokinase can directly break down fibrin, the protein involved in blood
clotting.
2. Nattokinase induces the formation of urokinase from its precursor, leading
to the production of plasminogen, which is an enzyme that degrades fibrin clots.
3. Nattokinase induces the tPA activity in tissues, which increases the
transformation of plasmin from plasminogen, increasing fibrinolysis.