What is Nattopur?

Nattopur assists people with thrombosis by providing nutrients to maintain normal
blood cholesterol levels and subsequently reduce blood clots in the blood vessels.

Thrombosis: The Silent Killer

Thrombosis is the formation of a blood clot (thrombus) inside a blood vessel, which leads to the obstruction of blood flow through the body. Lack of blood and, consequently, oxygen supply may result in severe tissue damage and organ failure. Thrombosis can happen in any blood vessel in the body and is thus classified based on the location of the body it occurs in; examples include venous thrombosis, arterial thrombosis, and microthrombosis. However, the prevalence of venous thrombosis is four times higher than arterial thrombosis.

Complications from Hypertension

Hypertension, otherwise known as high blood pressure, occurs when there is a hardening of arteries and the heart works harder to pump blood to the body. When blood is forced through, the high pressure can rupture molecules and cause the body to overreact and form unnecessary clots. This means that elevated blood pressure in the arteries is a major risk factor for cardiovascular diseases, such as a stroke or myocardinal infarction (more commonly known as a heart attack). It can also lead to hypertensive retionopathy and nephropathy. Hypertension’s significant impact on health means it can cause renal disease in addition to heart disease, making it one of the leading top ten causes of death. Worldwide, 1 out of 3 deaths is caused by ischemic heart diseases and since 2000, a heart attack has become the leading cause of death in the world with a stroke ranked closely as the second.

What is Natto?

Natto is fermented soybeans and has been a part of the Japanese cuisine for over a thousand years, believed to be health enhancing. Dr. Hiroyuki Sumi, a Japanese medical researcher, discovered in 1980 that natto had effective antithrombotic properties. The extraction of the enzyme produced during the fermentation of natto was coined as nattokinase, and it has demonstrated strong activities against thrombosis.

The Actions of Nattokinase

Since nattokinase can be consumed orally, it uses the following three diverse physiological and cellular pathways to increase the body’s defense against thrombosis:

1. Nattokinase can directly break down fibrin, the protein involved in blood clotting.

2. Nattokinase induces the formation of urokinase from its precursor, leading to the production of plasminogen, which is an enzyme that degrades fibrin clots.

3. Nattokinase induces the tPA activity in tissues, which increases the transformation of plasmin from plasminogen, increasing fibrinolysis.

Why Choose Nattopur Over Other Nattokinase Products? (“The Golden Recipe”)

Each of our capsule contains 2000FU nattokinase and the following other ingredients:

1. Red yeast: Red yeast, without aflatoxin, reduces blood cholesterol and neutral fat. Red yeast can thus increase organ function and detoxify blood.

2. Resveratrol: This polyphenolic compound is found in grape peels, red wine, peanuts, and berries. The natural plant-based detoxifying substance has various beneficial properties, including anti-aging, cardiovascular health protection, anti-oxidative effects, anti-inflammatory effects, anticancer effects, blood pressure regulation, nervous system protection, lipidoxidation prevention, platelet aggregation, and circulation regulation of the body’s lipids and protein levels.

3. Citrus extract: Rich in flavonoids, the extract has antiviral, antiinflammatory, and antispasmodic effects. The bioflavanoids can also help enhance the effect of vitamin C in the body, which strengthens collagen structure of the vessel wall and increases both vascular function and absorption of iron in the gastrointestinal tract.

This makes it a golden combination for our consumers.

Our Other Requirements for Processing Nattokinase

1. Vitamin K2-free: Vitamin K2 prevents osteoporosis, but it is also a key component in keeping the body’s natural ability for blood clotting.

2. Purine-free: Natto is a fermented product of soybeans, which contains high levels of purine. Nattokinase contains no purine and allows people with gout to consume this product.

3. Soy isoflavones-free: Soy isoflavones are phytoestrogens with specific recommended levels for consumption. To prevent an overdose in estrogen, soy isoflavones were removed.

4. Odor-free: The specific aroma of natto is rarely accepted by those who are not accustomed to the Japanese dish and was thus removed.




















Caution to Nattopur Consumers:

• The Japanese Nattokinase Association has a recommended intake based on the typical Japanese diet, which is a daily intake of 50g of natto. This is equivalent to 2000 fibrinolytic units (FU).

• Each user needs to adjust their consumption of the Nattopur products based on their medical conditions. The recommended starting dose is 4000 FU, which would be 2 capsules a day.

• Users with past eye surgeries or injuries may experience discomfort or pain because of the thrombolytic process. If this occurs, consult your physician and reduce the intake.